Genetics Glossary


allele
One of two or more alternative forms of a gene. In diploid cells two alleles occupy the same locus on a homologous pair of chromosomes

centriole
Two cylindrical structures assembled from microtubules. During prophase the centrioles are doublicated and start migrating to opposite sides of the nucleus.

centromere
Central region on a chromosome. After replication the microtubules . During prophase the centrioles are doublicated and start to migrate to opposite sides of the nucleus.

chromatin
Dense complex consisting of double helix DNA and histones. Sub-structures are nucleosomes, which condense into chromatin fibers. See your textbook for illustration.

chromosome
A very long segment of DNA and associated proteins composed of genes which carry all or part of the hereditary information of the organism.

diploid
Two set of chromosomes. This means that there are also two copies of each gene. The DNA in somatic cells is diploid

eukaryotic
A eukaryotic cell has nucleus and cellular organelles such as mitochondria, rough ER smooth ER, Golgi etc.

DNA
See Sructure of DNA

gamete
A sperm or egg cell for sexual reproduction. Gamets are haploid cells which have only one copy of each chromosome.

gene
A segment of DNA which encodes am-RNA (which is translated into a protein), a t-RNA or a r-RNA. This segment of the DNA may include control sequences for the xpression of the gene.

genotype
The genetic make up of an individual, i.e. all the genes present in a person. Compare to phenotype.

haploid
Having only one copy of each chromosome. Sperm or egg cells (gametes)are haploid, compared to somatic cells which are diploid is located.

heterozygous
Having two different alleles of the same gene.

homologous chromosome
One of two copies of a chromosome . One copy is derived from the male parent and the other copy is derived from the female parent

homozygous
Having two identical alleles of the same gene.

kinetochore
Specialized proteins near the centromer region of prophase chromosomes. They serve as attachment anchor for the microtubules radiating out from the centrioles .

locus
The position on a chromosome where a gene is located.

meiosis
Process of cellular division which produces egg or sperm cells. After replication an initially diploid cell undergoes two divisions, resulting in four haploid daughter cells.

mitosis
Division of the cellular nucleus containing replicated DNA. During mitosis the replicated chromosomes are separated into two identical sets , one for each daughter cell. Cell proliferation proceeds via mitosis.

microfilaments
filamentous protein fibers. Like microtubles microfilaments are part of the cytoskeleton which supports cell shape. They also play a role in muscle contraction, since muscle fibers are composed of microfilaments

microtubule
Cylindrically shaped protein fibers. Microtubles are part of the cytoskeleton which supports cell shape, they also play a role in cellular motility and growth

nucleotide
Basic building block molecule of DNA or RNA. Consists of ribose or deoxyribose, nucleic acid base and phosphate. See DNA Structure

phenotype
The traits that an individual expresses, e.g. a flower has three genotypes AA, Aa and aa , but only two phenotypes, purple and white.

prokariotic
A prokariotic cell has no nucleus and no cellular organelles. Bacteria are prokariotes.

somatic cells
Any cell of an organism except cells which form gametes